Wenxin Keli (稳心颗粒) is a Chinese patent medicine used in China for specified cardiovascular symptoms and arrhythmias under the conditions described in its approved product information together with relevant clinical evidence.
Important Safety Information #
Do not use if: #
- You have a bradyarrhythmia or abnormally slow heart rhythm.
- You are allergic to Wenxin Keli or any of its ingredients.
Use Wenxin Keli with caution during pregnancy
If you have a serious cardiovascular condition, severe or worsening symptoms, or other significant medical conditions, Wenxin Keli should not be used as a substitute for appropriate medical evaluation and treatment.
Possible Side Effects: #
- Gastrointestinal
- Nausea
- Vomiting
- Abdominal discomfort
- Abdominal bloating
- Abdominal pain
- Diarrhea
Neurological #
- Dizziness
- Headache
Skin and Allergic Reaction #
- Rash
- Itching
Other Reported Reactions #
- Chest tightness
Not everyone who uses Wenxin Keli will experience these reactions, and this list should not be interpreted as a prediction of individual risk.
If you develop a new or concerning symptom after taking Wenxin Keli, stop and seek appropriate medical advice when necessary.
Clinical Safety Evidence #
Wenxin Keli has been evaluated in clinical research as well as through post-marketing safety monitoring. #
One of the better-known clinical studies was a randomized, double-blind, placebo-controlled, multicenter trial involving 1,200 participants with frequent premature ventricular contractions (PVCs).
Participants received Wenxin Keli or placebo for four weeks. The investigators assessed vital signs, laboratory measurements and electrocardiographic parameters as part of the safety evaluation.
The study reported no severe adverse effects attributable to Wenxin Keli during the trial period.
This is useful clinical safety information, but it should be interpreted within the limits of the study. A four-week clinical trial cannot establish the absence of rare, delayed, or long-term adverse reactions in all populations.
Several reviews of the clinical literature have noted limitations in parts of the evidence base, including: #
- Short treatment or follow-up periods
- Small study populations in some trials
- Variable methodological quality
- Incomplete adverse-event reporting in some studies
- Limited evidence for some patient populations
The core contraindications, adverse reactions, precautions, ingredients, administration instructions and product identity information on this page are based on the current product information published by Shandong Buchang Pharmaceutical Co., Ltd., the marketing authorization holder and manufacturer of Wenxin Keli with Chinese drug approval number Z10950026.
